Outplays Jonathan Taylor on MNF
McCaffrey handled 21 carries for 117 yards and caught six of eight targets for 29 yards and a pair of touchdowns in Monday's 48-27 win over Indianapolis.
McCaffrey and the Colts' Jonathan Taylor headlined a matchup featuring two of the league's top running backs on Monday Night Football. CMC got the better of Taylor (16-46-1) despite facing the stiffer of the two defenses, doubling the latter's yards from scrimmage and scoring output in a winning effort. McCaffrey pushed his rushing total over the 1,000-yard mark for the season while sitting 151 yards shy of doing the same as a receiver with two games left in the regular season. With the 49ers having a potential path to the No. 1 seed in the NFC, fantasy managers can expect the team to lean heavily on McCaffrey against the Bears in Week 17, especially if star TE George Kittle (ankle) is unable to suit up.
More San Francisco 49ers Fantasy Football News
Ricky Pearsall
WR | SF
To be limited Wednesday
Coach Kyle Shanahan said Pearsall (knee/ankle) will be limited at practice Wednesday, Matt Maiocco of NBC Sports Bay Area reports.
George Kittle
TE | SF
No practice Wednesday
Coach Kyle Shanahan said Kittle (ankle) won't practice Wednesday but "has a chance" to play Sunday against the Bears, Nick Wagoner of ESPN.com reports.
George Kittle
TE | SF
Avoids high-ankle sprain
Kittle was diagnosed with a low-to-mid-grade ankle sprain following an MRI on Tuesday, Jeremy Fowler of ESPN.com reports.
Jake Tonges
TE | SF
Steps in for injured starter Monday
Tonges caught one of two targets for seven yards in Monday's 48-27 win over the Colts.
Brian Robinson Jr.
RB | SF
Gains 20 yards Monday
Robinson rushed five times for 20 yards while failing to catch his only target in Monday's 48-27 win over Indianapolis.
Demarcus Robinson
WR | SF
Scores first TD with SF
Robinson had two receptions on as many targets for 22 yards and a touchdown in Monday's 48-27 win over Indianapolis.
Kendrick Bourne
WR | SF
Gains 27 yards in spot-start
Bourne had three receptions on five targets for 27 yards in Monday's 48-27 win over the Colts.
Jauan Jennings
WR | SF
Scoring binge continues Monday
Jennings corralled five of six targets for 71 yards and a touchdown in Monday's 48-27 win over the Colts.
George Kittle
TE | SF
Severity of ankle injury TBD
San Francisco coach Kyle Shanahan said after Monday's 48-27 win against the Colts that it's too early to know the severity of Kittle's ankle injury, Nick Wagoner of ESPN.com reports.
Brock Purdy
QB | SF
Career night on MNF
Purdy completed 25 of 34 pass attempts for 295 yards, five touchdowns and one interception while taking two carries for 11 yards in Monday's 48-27 rout of the Colts.